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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
12.12
Human Site:
T345
Identified Species:
20.51
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
T345
S
T
G
L
Q
A
D
T
E
A
K
M
K
G
L
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
T345
S
T
G
L
Q
A
D
T
E
A
K
M
K
G
L
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
T351
S
T
G
L
Q
A
D
T
E
A
K
M
K
G
L
Dog
Lupus familis
XP_538417
666
74288
A350
S
T
G
L
Q
A
E
A
D
A
K
I
K
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
A346
S
T
G
L
Q
A
E
A
E
A
K
M
K
G
L
Rat
Rattus norvegicus
Q66HE5
630
69934
G324
E
Q
E
A
L
R
E
G
G
H
P
S
G
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
P345
G
L
Q
A
E
A
E
P
K
G
K
G
L
A
K
Chicken
Gallus gallus
Q9IA88
798
88848
Y337
Y
N
H
F
A
A
I
Y
Y
L
L
L
E
R
L
Frog
Xenopus laevis
NP_001088596
570
64876
R264
L
M
V
N
P
E
R
R
A
T
L
A
D
V
A
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
I667
L
Y
Q
Q
E
Q
Q
I
L
H
Q
Q
I
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
S968
N
S
G
A
S
G
G
S
S
S
N
S
R
C
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
L511
S
I
N
V
S
S
S
L
G
Q
H
P
A
G
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
G205
E
V
D
V
W
S
C
G
V
I
L
Y
A
L
L
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
E324
P
D
L
K
P
H
P
E
E
E
N
E
N
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
86.6
0
N.A.
13.3
13.3
0
0
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
33.3
26.6
0
13.3
N.A.
40
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
22
8
50
0
15
8
36
0
8
15
8
15
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
8
0
0
0
22
0
8
0
0
0
8
8
8
% D
% Glu:
15
0
8
0
15
8
29
8
36
8
0
8
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
43
0
0
8
8
15
15
8
0
8
8
43
0
% G
% His:
0
0
8
0
0
8
0
0
0
15
8
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
8
0
8
0
8
8
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
8
0
43
0
36
0
8
% K
% Leu:
15
8
8
36
8
0
0
8
8
8
22
8
8
8
50
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
29
0
0
0
% M
% Asn:
8
8
8
8
0
0
0
0
0
0
15
0
8
8
8
% N
% Pro:
8
0
0
0
15
0
8
8
0
0
8
8
0
0
0
% P
% Gln:
0
8
15
8
36
8
8
0
0
8
8
8
0
8
0
% Q
% Arg:
0
0
0
0
0
8
8
8
0
0
0
0
8
8
0
% R
% Ser:
43
8
0
0
15
15
8
8
8
8
0
15
0
0
8
% S
% Thr:
0
36
0
0
0
0
0
22
0
8
0
0
0
0
0
% T
% Val:
0
8
8
15
0
0
0
0
8
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
8
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _